Recombinant Human IL2Ra/CD25 Protein (His Tag)

Measured by its ability to inhibit IL2-induced proliferation of M07e cells. The ED50 for this effect is 0.2-1.2 μg/mL in the presence of 30ng/mL of recombinant human IL2.

Measured by its ability to inhibit IL2-induced proliferation of M07e cells. The ED<sub>50</sub> for this effect is 0.2-1.2 μg/mL in the presence of 30ng/mL of recombinant human IL2.
Manufactured by:Elabscience
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Recombinant Human IL2Ra/CD25 Protein (His Tag)

Recombinant Human IL2Ra/CD25 Protein (His Tag) supplied by Elabscience with collaborator-provided technical specifications.

SKU:
ABM16711-1
Product type
Recombinant Proteins
TargetIL2Ra/CD25
Species / reactivityHuman
Purity>97% by SDS-PAGE

Manufacturer provenance

Manufactured by:
Elabscience
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Recombinant Human IL2Ra/CD25 Protein (His Tag) is a research-use recombinant protein from Elabscience preparation representing IL2Ra/CD25 supplied as Lyophilized. Review the expression, purity, formulation and storage specifications below before selecting it for an assay or functional workflow.

Key facts & specifications
Research areas
immunology
Also known as
IMD, IDDM, IL2RA, CD25, IDDM10, IL2R, IMD41, TCGFR, p55, IL-2 receptor subunit alpha, IL-2R subunit alpha, IL2-RA, IL-2-RA, IL-2Rα, Interleukin-2 receptor subunit alpha, TAC antigen, Tac, p55, IL-2R&, alpha, alpha chain, CD25 antigen, IL 2 receptor alpha subunit, IL2 RA, Interleukin 2 receptor, Interleukin 2 receptor alpha, Interleukin 2 receptor alpha chain, t-cell growth factor receptor
Modification
C-His
Molecular weight
23.3 kDa
Form / buffer
Lyophilized
Activity
1. Using the Octet RED System, the affinity constant (Kd) of Human IL2RA-his bound to Human IL2 was 35nM. 2. Measured by its ability to inhibit IL2-dependent proliferation of MO7e human megakaryocytic leukemic cells in the presence of 30 ng/mL of recombinant human IL-2. The ED50 for this effect is 0.15-0.75μg/mL.
Endotoxin level
< 1.0 EU per μg of the protein as determined by the LAL method.
Sequence
Met 1-Cys 213
Technical note
Please refer to the printed manual for detailed information.
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

SpeciesBioactivityBindingCell-BasedIn VivoELISA Capture
Human
Identifiers & database references
Supplier SKU / catalogue number
PKSH031814_100ug
Gene symbol
IL2Ra/CD25
Gene ID
3559
UniProt accession
NP_000408.1
Storage, stability & shipping
Shelf life
12 months
Shipped at
This product is provided as lyophilized powder which is shipped with ice packs.
Short-term storage
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Long-term storage
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Aliquoting guidance
Reconstitute entire vial immediately. Aliquot working stock; avoid repeated freeze-thaw.
Compliance & documents
REACH compliant
Yes
ISO certifications
ISO 9001:2015, ISO 14001:2015, ISO 45001:2018
Datasheet
Open datasheet
Product manual
Open manual
Safety data sheet
Open SDS
Frequently asked questions
Who manufactured this product?

This product is manufactured by Elabscience and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Elabscience
£432.00£345.60