Rat BAD (BCL-2 Associated Death Promoter) CLIA Kit with collaborator-tested sample matrix evidence from Elabscience.
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Rat BAD (BCL-2 Associated Death Promoter) CLIA Kit from Elabscience is intended for research workflows involving BAD. Review the listed specifications and supporting documents to confirm compatibility with the intended method.
This product is manufactured by Elabscience and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
BCL2 associated agonist of cell death (BAD) is a pro-apoptotic BH3-only BCL2-family regulator whose activity is strongly controlled by phosphorylation. When active, BAD can engage anti-apoptotic BCL2-family proteins and shift mitochondrial signalling toward intrinsic apoptosis. This page groups ABMIUM catalogue reagents for BAD signalling and cell-death research.
Biological function: BAD is regulated by phosphorylation at multiple serine residues. Survival signalling can promote phosphorylated BAD association with 14-3-3 proteins, limiting its pro-apoptotic activity. Dephosphorylated BAD can bind anti-apoptotic BCL2-family proteins such as BCL-XL and BCL2, favouring activation of the mitochondrial apoptosis programme.
