Manufactured by:Elabscience
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Human GDF15 (Growth Differentiation Factor 15) CLIA Kit

Human GDF15 (Growth Differentiation Factor 15) CLIA Kit with collaborator-tested sample matrix evidence from Elabscience.

SKU:
ABM10828-1
Product type
Assay Kits
TargetGDF15

Manufacturer provenance

Manufactured by:
Elabscience
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Human GDF15 (Growth Differentiation Factor 15) CLIA Kit from Elabscience is intended for research workflows involving GDF15. Review the listed specifications and supporting documents to confirm compatibility with the intended method.

Key facts & specifications
Research areas
Cancer, Cell Biology, Cardiovascular, Signal transduction
Also known as
GDF15,GDF-15,MIC-1,MIC1,NAG-1,PDF,PLAB,PTGFB,Macrophage inhibitory cytokine 1,NSAID-activated gene 1 protein (NAG-1),NSAID-regulated gene 1 protein (NRG-1),Placental TGF-beta,Placental bone morphogenetic protein,Prostate differentiation factor
Cross-reactivity
This kit recognizes Human GDF15 in samples.No significant cross-reactivity or interference between Human GDF15 and analogues was observed
Incubation temperature
2-8℃/-20℃
Assay type
CLIA Kits
Detection method
Chemiluminescence
Plate format
48-well microplate plates pre-coated with anti-GDF15 capture antibody
Technical note
This CLIA kit uses the Sandwich-CLIA principle. The micro CLIA plate provided in this kit has been pre-coated with an antibody specific to Human GDF15. Samples or Standards are added to the micro CLIA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for Human GDF15 and Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Human GDF15, biotinylated detection antibody and Avidin-HRP conjugate will appear luminescence. The Relative light unit (RLU) value is measured by the Chemiluminescence immunoassay analyzer at 425nm. The RLU value is positively associated with the concentration of Human GDF15. You can calculate the concentration of Human GDF15 in the samples by comparing the RLU value of the samples to the standard curve.
Identifiers & database references
Supplier SKU / catalogue number
E-CL-H0080_48T
Gene symbol
GDF15
Gene ID
9518
UniProt accession
Q99988
Storage, stability & shipping
Shelf life
12 months from shipping dates
Shipped at
Wet ice (2-8 degrees C)
Short-term storage
4 degrees C for up to 6 months; do not freeze pre-coated plate
Long-term storage
4 degrees C for up to 12 months
Aliquoting guidance
Lyophilised standards and detection antibody may be reconstituted and aliquoted; store reconstituted aliquots at -20 degrees C for up to 2 weeks
Compliance & documents
REACH compliant
Yes
ISO certifications
ISO 9001:2015, ISO 14001:2015, ISO 45001:2018
Datasheet
Open datasheet
Product manual
Open manual
Safety data sheet
Open SDS
Frequently asked questions
Who manufactured this product?

This product is manufactured by Elabscience and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

GDF15growth differentiation factor 15

View target guide

GDF15 identifies growth differentiation factor 15 in Homo sapiens (Human). This target record connects NCBI Gene 9518, UniProtKB Q99988 and related ABMIUM catalogue products.

Biological function: GDF15 is a secreted stress-responsive hormone/cytokine that communicates physiological stress to the brain. It binds GFRAL and forms a signalling complex with RET in brainstem neurons, producing responses that include reduced food intake and altered energy balance; circulating GDF15 is also widely studied in metabolic stress, pregnancy, cancer and cachexia.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
9518
UniProtKB
Q99988
Elabscience
£407.00£325.60