ASNS rabbit pAb from ELK Biotechnology
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ASNS rabbit pAb is a research-use antibody from ELK Biotechnology for studying ASNS in WB workflows with listed reactivity for Human, Mouse, Rat. Specifications and supporting documents below should be reviewed when planning the experiment.
The protein encoded by this gene is involved in the synthesis of asparagine. This gene complements a mutation in the temperature-sensitive hamster mutant ts11, which blocks progression through the G1 phase of the cell cycle at nonpermissive temperature. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2010],
| Specificity | This antibody detects endogenous levels of ASNS at Human/Mouse/Rat |
|---|---|
| Validation evidence captions | Western blot analysis of lysates from AD293 cells, primary antibody was diluted at 1:1000, 4°over night |
Fully tested in-house by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Species | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Mouse | |||||||
| Rat |
This product is manufactured by ELK Biotechnology and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
Asparagine synthetase (glutamine-hydrolyzing) (ASNS; glutamine-dependent asparagine synthetase) is a cytosolic enzyme that synthesizes L-asparagine from L-aspartate using glutamine and ATP. This catalogue-backed ABMIUM record links human ASNS (NCBI Gene 440; UniProt P08243) to research reagents.
Biological function: ASNS catalyzes ATP-dependent synthesis of L-asparagine from L-aspartate, using L-glutamine as the amide-nitrogen donor and producing L-glutamate, AMP and diphosphate. It is a central enzyme in de novo asparagine biosynthesis and amino-acid homeostasis.
