ABMIUM target intelligence

ABCE1

ATP binding cassette subfamily E member 1

ATP binding cassette subfamily E member 1 (ABCE1), also known as RNase L inhibitor, RLI or RLI1, is an ATP-binding protein linked to RNase L regulation and translation-associated ribosomal biology.

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OrganismMultiple species; representative: Homo sapiens (Human) NCBI Gene6059 UniProtP61221

ABMIUM research catalogue

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Research context & evidence

About ABCE1

Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.

Biology

Biological function

ABCE1 is an ATP-binding cassette family protein also known as RNase L inhibitor (RLI). NCBI records support inhibition of ribonuclease L in the 2-5A/RNase L pathway, while conserved-domain annotation places ABCE1/RLI1 in translation and ribosomal biogenesis-related ATPase biology.

Experimental context

Research context

ABCE1 is studied in antiviral-interferon pathway regulation, RNase L biology, protein synthesis and ribosome-associated processes. Experimental interpretation should distinguish these functions from membrane-transport roles of other ABC family members and should follow product-level validation.

Identifiers

Alternative names

Names used across publications, databases and supplier catalogues.

ATP-binding cassette sub-family E member 1ABC38OABPOK/SW-cl.40RLIRLI1RNASEL1RNASELIRNS4Iwu:fb34c09wu:fe47b01wu:fi09g07zgc:111906zgc:56045