Manufactured by:Boster Bio
ABMIUM Verified™RUO

Anti-FKBP52/FKBP4 Antibody Picoband®

Primary Antibody supplied by Boster Bio

SKU:
ABM24360-1
Product type
Primary Antibodies
TargetPeptidyl-prolyl cis-trans isomerase FKBP4
ApplicationsELISA, Flow Cytometry, IHC, IHC-P, WB
Species / reactivityHuman, Mouse, Rat

Manufacturer provenance

Manufactured by:
Boster Bio
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Anti-FKBP52/FKBP4 Antibody Picoband® is a research-use antibody from Boster Bio for studying Peptidyl-prolyl cis-trans isomerase FKBP4 in ELISA, Flow Cytometry, IHC, IHC-P, WB workflows with listed reactivity for Human, Mouse, Rat. Specifications and supporting documents below should be reviewed when planning the experiment.

Boster Bio Anti-FKBP52/FKBP4 Antibody Picoband® catalog # A02165-3. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

FK506-binding protein 4 is a protein that in humans is encoded by the FKBP4 gene. The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It has high structural and functional similarity to FK506-binding protein 1A (FKBP1A), but unlike FKBP1A, this protein does not have immunosuppressant activity when complexed with FK506. It interacts with interferon regulatory factor-4 and plays an important role in immunoregulatory gene expression in B and T lymphocytes. This encoded protein is known to associate with phytanoyl-CoA alpha-hydroxylase. It can also associate with two heat shock proteins (hsp90 and hsp70) and thus may play a role in the intracellular trafficking of hetero-oligomeric forms of the steroid hormone receptors. This protein correlates strongly with adeno-associated virus type 2 vectors (AAV) resulting in a significant increase in AAV-mediated transgene expression in human cell lines. Thus this encoded protein is thought to have important implications for the optimal use of AAV vectors in human gene therapy. The human genome contains several non-transcribed pseudogenes similar to this gene.

Product information

Key facts & specifications
Also known as
51 kDa FK506 binding protein; 52 kDa FK506 binding protein; 52 kDa FKBP; 59 kDa immunophilin; FK506 binding protein 4; FK506 binding protein 4; 59kDa; FKBP 4; FKBP 52; FKBP4; FKBP51; FKBP52; FKBP59; HBI; HSP binding immunophilin; Hsp56; Immunophilin FKBP52; p52; p59; PPIase; PPIase FKBP4; Rotamase
Host species
Rabbit
Clonality
Polyclonal
Isotype
Rabbit IgG
Cross-reactivity
No cross-reactivity with other proteins.
Dilution range
Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human FKBP52/FKBP4, which shares 94.7% amino acid (aa) sequence identity with mouse and rat FKBP4.
Observed band
56-59 kDa
Molecular weight
63692 MW
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Purification
Immunogen affinity purified.
Form / buffer
Lyophilized
Sequence fragment
A synthetic peptide corresponding to a sequence at the C-terminus of human FKBP52/FKBP4, which shares 94.7% amino acid (aa) sequence identity with mouse and rat FKBP4.
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

SpeciesWBIHCIHC-PIHC-FIF/ICCFlow CytometryELISAIP
Human
Mouse
Rat
Identifiers & database references
Supplier SKU / catalogue number
A02165-3
Gene symbol
FKBP4
Gene ID
2288
UniProt accession
Q02790
Storage, stability & shipping
Shelf life
At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.
Storage conditions
At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.
Shipped at
Ambient or cold-chain dependent on product format
Short-term storage
At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.
Long-term storage
At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.
Storage buffer
Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
Storage warning
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Compliance & documents
CE marked
No
Datasheet
Open datasheet
Safety data sheet
Open SDS
Frequently asked questions
Who manufactured this product?

This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Boster Bio
£328.00