Manufactured by:Elabscience
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Human ADAMTS4 (ADAM with Thrombospondin Type 1 Motif 4) CLIA Kit

Human ADAMTS4 (ADAM with Thrombospondin Type 1 Motif 4) CLIA Kit with collaborator-tested sample matrix evidence from Elabscience.

SKU:
ABM10885-1
Product type
Assay Kits
TargetADAMTS4

Manufacturer provenance

Manufactured by:
Elabscience
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Human ADAMTS4 (ADAM with Thrombospondin Type 1 Motif 4) CLIA Kit from Elabscience is intended for research workflows involving ADAMTS4. Review the listed specifications and supporting documents to confirm compatibility with the intended method.

Key facts & specifications
Research areas
Cancer, Cell Biology, Signal transduction
Also known as
ADAMTS4,ADAMTS-4,KIAA0688,UNQ769,PRO1563
Cross-reactivity
This kit recognizes Human ADAMTS4 in samples.No significant cross-reactivity or interference between Human ADAMTS4 and analogues was observed
Incubation temperature
2-8℃/-20℃
Assay type
CLIA Kits
Detection method
Chemiluminescence
Plate format
48-well microplate plates pre-coated with anti-ADAMTS4 capture antibody
Technical note
This CLIA kit uses the Sandwich-CLIA principle. The micro CLIA plate provided in this kit has been pre-coated with an antibody specific to Human ADAMTS4. Samples or Standards are added to the micro CLIA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for Human ADAMTS4 and Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Human ADAMTS4, biotinylated detection antibody and Avidin-HRP conjugate will appear luminescence. The Relative light unit (RLU) value is measured by the Chemiluminescence immunoassay analyzer at 425nm. The RLU value is positively associated with the concentration of Human ADAMTS4. You can calculate the concentration of Human ADAMTS4 in the samples by comparing the RLU value of the samples to the standard curve.
Identifiers & database references
Supplier SKU / catalogue number
E-CL-H0222_48T
Gene symbol
ADAMTS4
Gene ID
9507
UniProt accession
O75173
Storage, stability & shipping
Shelf life
12 months from shipping dates
Shipped at
Wet ice (2-8 degrees C)
Short-term storage
4 degrees C for up to 6 months; do not freeze pre-coated plate
Long-term storage
4 degrees C for up to 12 months
Aliquoting guidance
Lyophilised standards and detection antibody may be reconstituted and aliquoted; store reconstituted aliquots at -20 degrees C for up to 2 weeks
Compliance & documents
REACH compliant
Yes
ISO certifications
ISO 9001:2015, ISO 14001:2015, ISO 45001:2018
Datasheet
Open datasheet
Product manual
Open manual
Safety data sheet
Open SDS
Frequently asked questions
Who manufactured this product?

This product is manufactured by Elabscience and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

ADAMTS4ADAM metallopeptidase with thrombospondin type 1 motif 4

View target guide

ADAM metallopeptidase with thrombospondin type 1 motif 4 (ADAMTS4/ADAMTS-4), also known as aggrecanase-1, is an extracellular matrix metalloprotease strongly associated with proteoglycan turnover.

Biological function: ADAMTS4, also known as aggrecanase-1, is a secreted ADAMTS-family metalloprotease. Curated NCBI and reviewed UniProt annotations describe cleavage of aggrecan and cartilage oligomeric matrix protein (COMP); NCBI also reports brevican degradation.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
9507
UniProtKB
O75173
Elabscience
£407.00£325.60