ABMIUM target intelligence

ASGR1

asialoglycoprotein receptor 1

Asialoglycoprotein receptor 1 (ASGR1; ASGPR1) is the major hepatocyte subunit of the asialoglycoprotein receptor, a lectin receptor that removes desialylated plasma glycoproteins. This catalogue-backed ABMIUM record links human ASGR1 (NCBI Gene 432; UniProt P07306) to research reagents.

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OrganismMultiple species; representative: Homo sapiens (Human) NCBI Gene432 UniProtP07306

ABMIUM research catalogue

Research Products

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Research context & evidence

About ASGR1

Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.

Biology

Biological function

ASGR1 is a type II transmembrane C-type lectin receptor subunit expressed predominantly on hepatocytes. It recognizes terminal galactose and N-acetylgalactosamine on desialylated glycoproteins and promotes receptor-mediated endocytosis followed by lysosomal degradation, supporting serum glycoprotein homeostasis.

Experimental context

Research context

ASGR1/ASGPR1 is studied in hepatic glycoprotein clearance, receptor-mediated endocytosis, hepatocyte biology and liver-directed delivery research. Review each linked ABMIUM product for species, application, assay format and product-level validation before use.

Identifiers

Alternative names

Names used across publications, databases and supplier catalogues.

ASGPRASGPR1CLEC4H1HL-1