CD44 (phospho Ser706) rabbit pAb from ELK Biotechnology
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CD44 (phospho Ser706) rabbit pAb is a research-use antibody from ELK Biotechnology for studying CD44 in WB, ELISA workflows with listed reactivity for Human, Mouse, Rat. Specifications and supporting documents below should be reviewed when planning the experiment.
The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008],
| Specificity | Phospho-CD44 (S706) Polyclonal Antibody detects endogenous levels of CD44 protein only when phosphorylated at S706. |
|---|---|
| Validation evidence captions | Western Blot analysis of 3T3 cells using Phospho-CD44 (S706) Polyclonal Antibody | Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using CD44 (Phospho-Ser706) Antibody | Western blot analysis of lysates from NIH/3T3 cells treated with PMA 250ng/ml 5', using CD44 (Phospho-Ser706) Antibody. The lane on the right is blocked with the phospho peptide. |
Fully tested in-house by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Species | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Mouse | |||||||
| Rat |
This product is manufactured by ELK Biotechnology and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
CD44 identifies CD44 molecule (IN blood group) in Homo sapiens (Human). This target record connects NCBI Gene 960, UniProtKB P16070 and related ABMIUM catalogue products.
Biological function: CD44 is a cell-surface receptor involved in cell-cell interactions, adhesion and migration. It engages extracellular-matrix components such as hyaluronan and contributes to lymphocyte activation, recirculation and homing.
