Manufactured by:ELK Biotechnology
RUO

GAP1-InsP4 BP rabbit pAb

GAP1-InsP4 BP rabbit pAb from ELK Biotechnology

SKU:
ABM107079
Product type
Primary Antibody
TargetGAP1-InsP4 BP
ApplicationsWB, ELISA
Species / reactivityHuman, Mouse, Rat
Expression systemBlood,Brain,Peripheral blood,Platelet,Testis,
PurityThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Manufacturer provenance

Manufactured by:
ELK Biotechnology
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

GAP1-InsP4 BP rabbit pAb is a research-use antibody from ELK Biotechnology for studying GAP1-InsP4 BP in WB, ELISA workflows with listed reactivity for Human, Mouse, Rat. Specifications and supporting documents below should be reviewed when planning the experiment.

Background

This gene encodes a protein that binds inositol 1,3,4,5-tetrakisphosphate and stimulates the GTPase activity of Ras p21. This protein functions as a negative regulator of the Ras signalling pathway. It is localized to the cell membrane via a pleckstrin homology (PH) domain in the C-terminal region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],

Additional antibody information

Specificity GAP1-InsP4 BP Polyclonal Antibody detects endogenous levels of GAP1-InsP4 BP protein.
Validation evidence captions Western Blot analysis of various cells using GAP1-InsP4 BP Polyclonal Antibody | Western blot analysis of RASA3 Antibody. The lane on the right is blocked with the RASA3 peptide. | Western blot analysis of the lysates from HUVECcells using RASA3 antibody.
Key facts & specifications
Research areas
>>Ras signaling pathway
Also known as
RASA3; Ras GTPase-activating protein 3; GAP1(IP4BP); Ins P4-binding protein
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Immunogen
The antiserum was produced against synthesized peptide derived from human RASA3. AA range:247-296
Observed band
95kD
Cellular localization
Cell membrane.
Assay type
Antibody validation/application
Source organism
Rabbit
Concentration
1 mg/ml
Working concentration
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form / buffer
Liquid
Sequence fragment
AA range: 247-296
Quantity per pack
50µL/100µL
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

SpeciesWBIHCIFELISAIPFCMChIP
Human
Mouse
Rat
Identifiers & database references
Supplier SKU / catalogue number
ES2397
UniProt entry
Q14644
Storage, stability & shipping
Storage conditions
'-20°C/1 year
Long-term storage
'-20°C/1 year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Compliance & documents
CE marked
No
ISO certifications
ISO 9001
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by ELK Biotechnology and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ELK Biotechnology
£220.00