Manufactured by:Elabscience
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Recombinant Human CD86/B7-2 Protein (Val185Ile, His Tag)

Recombinant Human CD86/B7-2 Protein (Val185Ile, His Tag) supplied by Elabscience with collaborator-provided technical specifications.

SKU:
ABM18271-1
Product type
Recombinant Proteins
TargetCD86
Species / reactivityHuman
Purity>95% by SDS-PAGE

Manufacturer provenance

Manufactured by:
Elabscience
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Recombinant Human CD86/B7-2 Protein (Val185Ile, His Tag) is a research-use recombinant protein from Elabscience preparation representing CD86 supplied as Lyophilized. Review the expression, purity, formulation and storage specifications below before selecting it for an assay or functional workflow.

Key facts & specifications
Research areas
Microbiology, immunology, Stem cells
Also known as
LAB, ETC, FUN, CTLA-4 Counter-Receptor B, Early T-cell costimulatory molecule, CD28LG, B7-2, B7.2, B70, CD28LG2, LAB72, CD86, Activation B7-2 antigen, BU63, CTLA-4 Counter-Receptor B7.2, Early T-cell costimulatory molecule 1, ETC-1, FUN-1, T-lymphocyte activation antigen CD86, B7-2, Activation B7-2 antigen 3, B7 2, B72 antigen, B-lymphocyte activation antigen B7-2, B-lymphocyte activation antigen B7-2 2, CD28 antigen ligand 2, CD28 antigen ligand 2 2, Cd28l2, CD86 antigen, CD86 molecule, CLS1, CTLA-4 counter-receptor B7.2 2, FUN 1, Ly58, Ly-58, MB7, MB7-2, Membrane glycoprotein, MGC34413, TS/A-2
Modification
C-His
Molecular weight
26.7 kDa
Form / buffer
Lyophilized
Activity
Loaded Human B7-2-His on HIS1K Biosensor, can bind Mouse CTLA-4-Fc with an affinity constant of 5.65 nM as determined in BLI assay.
Endotoxin level
< 1.0 EU per μg of the protein as determined by the LAL method.
Sequence
Ala24-Pro247
Technical note
Please refer to the printed manual for detailed information.
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

SpeciesBioactivityBindingCell-BasedIn VivoELISA Capture
Human
Identifiers & database references
Supplier SKU / catalogue number
PKSH033722_10ug
Gene symbol
CD86
Gene ID
942
UniProt accession
AAH40261.1
Storage, stability & shipping
Shelf life
12 months
Shipped at
This product is provided as lyophilized powder which is shipped with ice packs.
Short-term storage
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Long-term storage
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Aliquoting guidance
Reconstitute entire vial immediately. Aliquot working stock; avoid repeated freeze-thaw.
Compliance & documents
REACH compliant
Yes
ISO certifications
ISO 9001:2015, ISO 14001:2015, ISO 45001:2018
Datasheet
Open datasheet
Product manual
Open manual
Safety data sheet
Open SDS
Frequently asked questions
Who manufactured this product?

This product is manufactured by Elabscience and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

CD86CD86 molecule

View target guide

CD86 identifies CD86 molecule in Homo sapiens (Human). This target record connects NCBI Gene 942, UniProtKB P42081 and related ABMIUM catalogue products.

Biological function: CD86 (B7-2) is an antigen-presenting-cell costimulatory molecule. It binds CD28 to support T-cell activation and also binds CTLA4, which negatively regulates T-cell activation and limits immune responses.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
942
UniProtKB
P42081
Elabscience
£43.00£34.40