Human AIRE (Autoimmune Regulator) CLIA Kit with collaborator-tested sample matrix evidence from Elabscience.
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Human AIRE (Autoimmune Regulator) CLIA Kit from Elabscience is intended for research workflows involving AIRE. Review the listed specifications and supporting documents to confirm compatibility with the intended method.
This product is manufactured by Elabscience and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
AIRE (autoimmune regulator) is a transcriptional regulator central to thymic immune tolerance, where it promotes expression of tissue-restricted antigens that support deletion of autoreactive T cells.
Biological function: AIRE regulates transcriptional programs in thymic epithelial cells and helps expose developing T cells to tissue-restricted self-antigens. Authoritative NCBI and UniProt evidence supports its chromatin-associated role in central self-tolerance and negative selection of autoreactive T cells.
