Manufactured by:Elabscience
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Human AGRN (Agrin) CLIA Kit

Human AGRN (Agrin) CLIA Kit with collaborator-tested sample matrix evidence from Elabscience.

SKU:
ABM10897-1
Product type
Assay Kits
TargetAGRN

Manufacturer provenance

Manufactured by:
Elabscience
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Human AGRN (Agrin) CLIA Kit from Elabscience is intended for research workflows involving AGRN. Review the listed specifications and supporting documents to confirm compatibility with the intended method.

Key facts & specifications
Research areas
Neuroscience, Signal transduction
Also known as
AGRN
Cross-reactivity
This kit recognizes Human AGRN in samples.No significant cross-reactivity or interference between Human AGRN and analogues was observed
Incubation temperature
2-8℃/-20℃
Assay type
CLIA Kits
Detection method
Chemiluminescence
Plate format
48-well microplate plates pre-coated with anti-AGRN capture antibody
Technical note
This CLIA kit uses the Sandwich-CLIA principle. The micro CLIA plate provided in this kit has been pre-coated with an antibody specific to Human AGRN. Samples or Standards are added to the micro CLIA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for Human AGRN and Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Human AGRN, biotinylated detection antibody and Avidin-HRP conjugate will appear luminescence. The Relative light unit (RLU) value is measured by the Chemiluminescence immunoassay analyzer at 425nm. The RLU value is positively associated with the concentration of Human AGRN. You can calculate the concentration of Human AGRN in the samples by comparing the RLU value of the samples to the standard curve.
Identifiers & database references
Supplier SKU / catalogue number
E-CL-H0244_48T
Gene symbol
AGRN
Gene ID
375790
UniProt accession
O00468
Storage, stability & shipping
Shelf life
12 months from shipping dates
Shipped at
Wet ice (2-8 degrees C)
Short-term storage
4 degrees C for up to 6 months; do not freeze pre-coated plate
Long-term storage
4 degrees C for up to 12 months
Aliquoting guidance
Lyophilised standards and detection antibody may be reconstituted and aliquoted; store reconstituted aliquots at -20 degrees C for up to 2 weeks
Compliance & documents
REACH compliant
Yes
ISO certifications
ISO 9001:2015, ISO 14001:2015, ISO 45001:2018
Datasheet
Open datasheet
Product manual
Open manual
Safety data sheet
Open SDS
Frequently asked questions
Who manufactured this product?

This product is manufactured by Elabscience and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

AGRNagrin

View target guide

Agrin (AGRN) is an extracellular matrix and synaptic organizer with a central role in neuromuscular junction formation and maintenance. This ABMIUM record links human AGRN (NCBI Gene 375790; reviewed UniProt O00468) to catalogue-backed research products.

Biological function: Agrin (AGRN) is a heparan-sulfate basal-lamina glycoprotein whose neuronal isoforms organize postsynaptic differentiation at the neuromuscular junction. Reviewed UniProt evidence describes AGRN-LRP4 complex formation, activation of MUSK and clustering of acetylcholine receptors, with additional isoform-dependent roles in neurite outgrowth and synapse biology.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
375790
UniProtKB
O00468
Elabscience
£407.00£325.60