TNFRSF1AFunctional association
Established TNF receptor (TNFR1) that mediates multiple inflammatory, survival and cell-death signalling responses.
ABMIUM target intelligence
Tumor necrosis factor
TNF encodes a multifunctional pro-inflammatory cytokine in the tumour necrosis factor superfamily. This target hub connects accepted names and identifiers with ABMIUM antibodies, ELISA kits and related assay products.
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Research context & evidence
Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.
TNF is produced as a membrane-associated cytokine and can be released in soluble form. Signalling through TNFRSF1A (TNFR1) and TNFRSF1B (TNFR2) contributes to regulation of inflammation, immune responses, cell survival, differentiation and cell death.
TNF is widely studied in inflammation, immune signalling, apoptosis, metabolic regulation and disease models. Reagent selection should be based on species, sample type, assay format, clone, application and the level of supporting validation.
Names used across publications, databases and supplier catalogues.
These relationships provide research context only. They do not establish product or application suitability.
Established TNF receptor (TNFR1) that mediates multiple inflammatory, survival and cell-death signalling responses.
High-affinity TNF receptor (TNFR2) involved in immune and metabolic signalling.
Interpretation: Relationships are provided as research context. They do not establish that a particular reagent is suitable for an experiment; consult the linked product data and validation evidence.