Manufactured by:ELK Biotechnology
RUO

TCF-3 rabbit pAb

TCF-3 rabbit pAb from ELK Biotechnology

SKU:
ABM109428
Product type
Primary Antibody
TargetTCF-3
ApplicationsWB, ELISA
Species / reactivityHuman, Mouse
Expression systemDetected in hair follicles and skin keratinocytes, and at lower levels in stomach epithelium.
PurityThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Manufacturer provenance

Manufactured by:
ELK Biotechnology
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

TCF-3 rabbit pAb is a research-use antibody from ELK Biotechnology for studying TCF-3 in WB, ELISA workflows with listed reactivity for Human, Mouse. Specifications and supporting documents below should be reviewed when planning the experiment.

Background

This gene encodes a member of the T cell factor/lymphoid enhancer factor family of transcription factors. These transcription factors are activated by beta catenin, mediate the Wnt signaling pathway and are antagonized by the transforming growth factor beta signaling pathway. The encoded protein contains a high mobility group-box DNA binding domain and participates in the regulation of cell cycle genes and cellular senescence. [provided by RefSeq, Nov 2010],

Additional antibody information

Specificity TCF-3 Polyclonal Antibody detects endogenous levels of TCF-3 protein.
Validation evidence captions Western blot analysis of TCF7L1 Antibody. The lane on the right is blocked with the TCF7L1 peptide. | Western blot analysis of the lysates from HUVECcells using TCF7L1 antibody.
Key facts & specifications
Research areas
>>Wnt signaling pathway, >>Hippo signaling pathway, >>Adherens junction, >>Melanogenesis, >>Cushing syndrome, >>Alcoholic liver disease, >>Salmonella infection, >>Human papillomavirus infection, >>Kaposi sarcoma-associated herpesvirus infection, >>Pathways in cancer, >>Colorectal cancer, >>Endometrial cancer, >>Prostate cancer, >>Thyroid cancer, >>Basal cell carcinoma, >>Acute myeloid leukemia, >>Breast cancer, >>Hepatocellular carcinoma, >>Gastric cancer, >>Arrhythmogenic right ventricular cardiomyopathy
Also known as
TCF7L1; TCF3; Transcription factor 7-like 1; HMG box transcription factor 3; TCF-3
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen
The antiserum was produced against synthesized peptide derived from human TCF7L1. AA range:321-370
Observed band
63kD
Cellular localization
Nucleus.
Assay type
Antibody validation/application
Source organism
Rabbit
Concentration
1 mg/ml
Working concentration
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form / buffer
Liquid
Sequence fragment
AA range: 321-370
Quantity per pack
50µL/100µL
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

SpeciesWBIHCIFELISAIPFCMChIP
Human
Mouse
Identifiers & database references
Supplier SKU / catalogue number
ES7682
UniProt entry
Q9HCS4
Storage, stability & shipping
Storage conditions
'-20°C/1 year
Long-term storage
'-20°C/1 year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Compliance & documents
CE marked
No
ISO certifications
ISO 9001
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by ELK Biotechnology and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ELK Biotechnology
£220.00