ALDH3A1 rabbit pAb from ELK Biotechnology
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ALDH3A1 rabbit pAb is a research-use antibody from ELK Biotechnology for studying ALDH3A1 in WB, ELISA workflows with listed reactivity for Human, Rat. Specifications and supporting documents below should be reviewed when planning the experiment.
Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008],
| Specificity | ALDH3A1 Polyclonal Antibody detects endogenous levels of ALDH3A1 protein. |
|---|---|
| Validation evidence captions | Western Blot analysis of extracts from A549, K562 cells, using ALDH3A1 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000 | Western blot analysis of lysates from A549 cells, using ALDH3A1 antibody. |
Fully tested in-house by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Species | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Rat |
This product is manufactured by ELK Biotechnology and sold through ABMIUM without relabelling.
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Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
ALDH3A1 (aldehyde dehydrogenase 3 family member A1), also called the dimeric NADP-preferring aldehyde dehydrogenase, is a cytoplasmic enzyme that oxidises aromatic and medium-chain aldehydes. It is studied in aldehyde detoxification, lipid-peroxidation stress and corneal oxidative-protection biology.
Biological function: ALDH3A1 forms a cytoplasmic homodimer and preferentially oxidises aromatic and medium-chain saturated or unsaturated aldehydes to corresponding acids. This activity contributes to reactive-carbonyl detoxification and has been linked to protection against UV- and 4-hydroxynonenal-associated oxidative damage in the cornea.
