Manufactured by:ELK Biotechnology
RUO

MYL3 rabbit pAb

MYL3 rabbit pAb from ELK Biotechnology

SKU:
ABM107293
Product type
Primary Antibody
TargetMYL3
ApplicationsWB, IHC, ELISA
Species / reactivityHuman, Rat, Mouse
Expression systemHeart,Skeletal muscle,
PurityThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Manufacturer provenance

Manufactured by:
ELK Biotechnology
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

MYL3 rabbit pAb is a research-use antibody from ELK Biotechnology for studying MYL3 in WB, IHC, ELISA workflows with listed reactivity for Human, Rat, Mouse. Specifications and supporting documents below should be reviewed when planning the experiment.

Background

MYL3 encodes myosin light chain 3, an alkali light chain also referred to in the literature as both the ventricular isoform and the slow skeletal muscle isoform. Mutations in MYL3 have been identified as a cause of mid-left ventricular chamber type hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008],

Additional antibody information

Specificity MYL3 Polyclonal Antibody detects endogenous levels of MYL3 protein.
Validation evidence captions Western Blot analysis of various cells using MYL3 Polyclonal Antibody | Western blot analysis of the lysates from HeLa cells using MYL3 antibody. | Immunohistochemical analysis of paraffin-embedded human Gastric adenocarcinoma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
Key facts & specifications
Research areas
>>Cardiac muscle contraction, >>Adrenergic signaling in cardiomyocytes, >>Apelin signaling pathway, >>Hypertrophic cardiomyopathy, >>Dilated cardiomyopathy
Also known as
MYL3; Myosin light chain 3; Cardiac myosin light chain 1; CMLC1; Myosin light chain 1; slow-twitch muscle B/ventricular isoform; MLC1SB; Ventricular/slow twitch myosin alkali light chain
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen
The antiserum was produced against synthesized peptide derived from human MYL3. AA range:71-120
Observed band
22kD
Cellular localization
cytosol,muscle myosin complex,myosin complex,sarcomere,A band,I band,
Assay type
Antibody validation/application
Source organism
Rabbit
Concentration
1 mg/ml
Working concentration
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form / buffer
Liquid
Sequence fragment
AA range: 71-120
Quantity per pack
50µL/100µL
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

SpeciesWBIHCIFELISAIPFCMChIP
Human
Rat
Mouse
Identifiers & database references
Supplier SKU / catalogue number
ES2876
UniProt entry
P08590
Storage, stability & shipping
Storage conditions
'-20°C/1 year
Long-term storage
'-20°C/1 year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Compliance & documents
CE marked
No
ISO certifications
ISO 9001
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by ELK Biotechnology and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

MYL3myosin light chain 3

View target guide

MYL3 identifies myosin light chain 3 in Homo sapiens (Human). This target record connects NCBI Gene 4634, UniProtKB P08590 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
4634
UniProtKB
P08590
ELK Biotechnology
£220.00