MAGE-C2 rabbit pAb

MAGE-C2 rabbit pAb

MAGE-C2 rabbit pAb
Manufactured by:ELK Biotechnology
RUO

MAGE-C2 rabbit pAb

MAGE-C2 rabbit pAb from ELK Biotechnology

SKU:
ABM107235
Product type
Primary Antibody
TargetMAGE-C2
ApplicationsWB, ELISA
Species / reactivityHuman, Rat, Mouse
Expression systemNot expressed in normal tissues, except in germ cells in the seminiferous tubules and in Purkinje cells of the cerebellum. Expressed in various tumors, including melanoma, lymphoma, as well as pancreatic cancer, mammary gland cancer, non-small cell lung cancer and liver cancer. In hepatocellular carcinoma, there is an inverse correlation between tumor differentiation and protein expression, i.e. the lower the differentiation, the higher percentage of expression.
PurityThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Manufacturer provenance

Manufactured by:
ELK Biotechnology
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

MAGE-C2 rabbit pAb is a research-use antibody from ELK Biotechnology for studying MAGE-C2 in WB, ELISA workflows with listed reactivity for Human, Rat, Mouse. Specifications and supporting documents below should be reviewed when planning the experiment.

Background

This gene is a member of the MAGEC gene family. It is not expressed in normal tissues, except for testis, and is expressed in tumors of various histological types. This gene and the other MAGEC genes are clustered on chromosome Xq26-q27. [provided by RefSeq, Oct 2009],

Additional antibody information

Specificity MAGE-C2 Polyclonal Antibody detects endogenous levels of MAGE-C2 protein.
Validation evidence captions Western Blot analysis of various cells using MAGE-C2 Polyclonal Antibody diluted at 1:1000 | Western Blot analysis of 293 cells using MAGE-C2 Polyclonal Antibody diluted at 1:1000 | Western blot analysis of mouse-brain HELA KB SH-SY5Y 293T 3T3 lysis using MAGE-C2 antibody. Antibody was diluted at 1:1000 | Western blot analysis of MAGEC2 Antibody. The lane on the right is blocked with the MAGEC2 peptide.
Key facts & specifications
Research areas
Antibody Research
Also known as
MAGEC2; HCA587; MAGEE1; Melanoma-associated antigen C2; Cancer/testis antigen 10; CT10; Hepatocellular carcinoma-associated antigen 587; MAGE-C2 antigen; MAGE-E1 antigen
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Immunogen
Synthesized peptide derived from MAGE-C2 . at AA range: 160-240
Observed band
41kD
Cellular localization
Cytoplasm . Nucleus . Nuclear in germ cells. Cytoplasmic in well-differentiated hepatocellular carcinoma, nuclear in moderately- and poorly-differentiated hepatocellular carcinoma.
Assay type
Antibody validation/application
Source organism
Rabbit
Concentration
1 mg/ml
Working concentration
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form / buffer
Liquid
Sequence fragment
AA range: 160-240
Quantity per pack
50µL/100µL
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

SpeciesWBIHCIFELISAIPFCMChIP
Human
Rat
Mouse
Identifiers & database references
Supplier SKU / catalogue number
ES2741
UniProt entry
Q9UBF1
Storage, stability & shipping
Storage conditions
'-20°C/1 year
Long-term storage
'-20°C/1 year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Compliance & documents
CE marked
No
ISO certifications
ISO 9001
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by ELK Biotechnology and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ELK Biotechnology
£220.00