MK12 rabbit pAb
Manufactured by:ELK Biotechnology
RUO

MK12 rabbit pAb

MK12 rabbit pAb from ELK Biotechnology

SKU:
ABM102783
Product type
Primary Antibody
TargetMK12
ApplicationsWB, ELISA
Species / reactivityHuman, Mouse, Rat
Expression systemHighly expressed in skeletal muscle and heart.
PurityThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Manufacturer provenance

Manufactured by:
ELK Biotechnology
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

MK12 rabbit pAb is a research-use antibody from ELK Biotechnology for studying MK12 in WB, ELISA workflows with listed reactivity for Human, Mouse, Rat. Specifications and supporting documents below should be reviewed when planning the experiment.

Background

Activation of members of the mitogen-activated protein kinase family is a major mechanism for transduction of extracellular signals. Stress-activated protein kinases are one subclass of MAP kinases. The protein encoded by this gene functions as a signal transducer during differentiation of myoblasts to myotubes. [provided by RefSeq, Jul 2008],

Additional antibody information

Specificity MK12 Polyclonal Antibody detects endogenous levels of protein.
Validation evidence captions Western blot analysis of lysates from DU145 cells, primary antibody was diluted at 1:1000, 4°over night
Key facts & specifications
Research areas
>>Endocrine resistance, >>MAPK signaling pathway, >>Rap1 signaling pathway, >>FoxO signaling pathway, >>Sphingolipid signaling pathway, >>Oocyte meiosis, >>Cellular senescence, >>Adrenergic signaling in cardiomyocytes, >>VEGF signaling pathway, >>Osteoclast differentiation, >>Signaling pathways regulating pluripotency of stem cells, >>Platelet activation, >>Neutrophil extracellular trap formation, >>Toll-like receptor signaling pathway, >>NOD-like receptor signaling pathway, >>RIG-I-like receptor signaling pathway, >>C-type lectin receptor signaling pathway, >>IL-17 signaling pathway, >>Th1 and Th2 cell differentiation, >>Th17 cell differentiation, >>T cell receptor signaling pathway, >>Fc epsilon RI signaling pathway, >>TNF signaling pathway, >>Leukocyte transendothelial migration, >>Thermogenesis, >>Neurotrophin signaling pathway, >>Retrograde endocannabinoid signaling, >>Dopaminergic synapse, >>Inflammatory mediator regulation of TRP channels, >>GnRH signaling pathway, >>Progesterone-mediated oocyte maturation, >
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
WB 1:500-2000 ELISA 1:5000-20000
Immunogen
Synthesized peptide derived from human protein . at AA range: 70-150
Observed band
40kD
Cellular localization
Cytoplasm. Nucleus. Mitochondrion. Mitochondrial when associated with SH3BP5. In skeletal muscle colocalizes with SNTA1 at the neuromuscular junction and throughout the sarcolemma (By similarity). .
Assay type
Antibody validation/application
Source organism
Rabbit
Concentration
1 mg/ml
Working concentration
WB 1:500-2000 ELISA 1:5000-20000
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form / buffer
Liquid
Sequence fragment
AA range: 70-150
Quantity per pack
50µL/100µL
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

SpeciesWBIHCIFELISAIPFCMChIP
Human
Mouse
Rat
Identifiers & database references
Supplier SKU / catalogue number
ES10560
UniProt entry
P53778
Storage, stability & shipping
Storage conditions
'-20°C/1 year
Long-term storage
'-20°C/1 year
Storage buffer
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Compliance & documents
CE marked
No
ISO certifications
ISO 9001
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by ELK Biotechnology and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ELK Biotechnology
£220.00