Manufactured by:Elabscience
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Recombinant Human CASP8 Protein(Trx Tag)

Recombinant Human CASP8 Protein(Trx Tag) supplied by Elabscience with collaborator-provided technical specifications.

SKU:
ABM13899-1
Product type
Recombinant Proteins
TargetCASP8
Species / reactivityHuman
Purity>90% by SDS-PAGE

Manufacturer provenance

Manufactured by:
Elabscience
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Recombinant Human CASP8 Protein(Trx Tag) is a research-use recombinant protein from Elabscience preparation representing CASP8 supplied as Lyophilized. Review the expression, purity, formulation and storage specifications below before selecting it for an assay or functional workflow.

Key facts & specifications
Research areas
Cancer, Cell Biology, Metabolism
Also known as
ALPS2B, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein, Apoptotic cysteine protease, Apoptotic protease Mch-5, Apoptotic protease Mch5, CAP4, CASP-8, CASP8, CASP8, Caspase 8, Caspase 8 apoptosis related cysteine peptidase, Caspase-8 subunit p10, CED 3, FADD Like ICE, FADD-homologous ICE/CED-3-like protease, FADD-like ICE, FLICE, FLJ17672, ICE-like apoptotic protease 5, MACH alpha 1/2/3 protein, MACH, MACH beta 1/2/3/4 protein, MCH5, MGC78473, MORT1 associated ced 3 homolog, MORT1-associated CED-3 homolog, OTTHUMP00000163717, OTTHUMP00000163720, OTTHUMP00000163724, OTTHUMP00000163725, OTTHUMP00000165062, OTTHUMP00000165063, OTTHUMP00000165064, OTTHUMP00000206552, OTTHUMP00000206582
Modification
N-Trx
Molecular weight
37.3 kDa
Form / buffer
Lyophilized
Endotoxin level
< 10 EU/mg of the protein as determined by the LAL method
Sequence
Ser217-Asp374
Technical note
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

SpeciesBioactivityBindingCell-BasedIn VivoELISA Capture
Human
Identifiers & database references
Supplier SKU / catalogue number
PDEH100561_100ug
Gene symbol
CASP8
Gene ID
841
UniProt accession
Q14790
Storage, stability & shipping
Shelf life
12 months
Shipped at
This product is provided as lyophilized powder which is shipped with ice packs.
Short-term storage
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Long-term storage
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Aliquoting guidance
Reconstitute entire vial immediately. Aliquot working stock; avoid repeated freeze-thaw.
Compliance & documents
REACH compliant
Yes
ISO certifications
ISO 9001:2015, ISO 14001:2015, ISO 45001:2018
Datasheet
Open datasheet
Product manual
Open manual
Safety data sheet
Open SDS
Frequently asked questions
Who manufactured this product?

This product is manufactured by Elabscience and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

CASP8caspase 8

View target guide

CASP8 identifies caspase 8 in Homo sapiens (Human). This target record connects NCBI Gene 841, UniProtKB Q14790 and related ABMIUM catalogue products.

Biological function: Caspase-8 (CASP8; FLICE/MACH) is an initiator cysteine protease activated in death-receptor signalling complexes. It cleaves downstream caspases to promote extrinsic apoptosis and also participates in regulated cell-death and inflammatory signalling.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
841
UniProtKB
Q14790
Elabscience
£364.00£291.20