ABM-20054
CollaboratorElabscience
Target
TNFR1/TNFRSF1APurity
>90% by SDS-PAGEMol. weight
47.9 kDaActivity
1. Measured by its ability to inhibit TNFα-mediated cytot...Species
Rat
1. Measured by its ability to inhibit TNFα-mediated cytotoxicity in L-929 mouse fibroblast cells in the presence of metabolic inhibitor actinomycin D. The ED50 for this effect is typically 3-30 ng/mL in the presence of 0.05 ng/mL of ratTNFα. 2. Immobilized mouse TNFa (80-235) at 10 μg/ml (100 μl/well) can bind rat TNFRSF1A-FcThe EC50 of rat TNFRSF1A-Fc is 0.08-0.20 μg/ml.HEK293 Cells< 1.0 EU per μg of the protein as determined by the LAL method.