ABM-16801
CollaboratorElabscience
Target
VEGFR2/Flk-1/KDRPurity
>97% by SDS-PAGEMol. weight
84.6 kDaActivity
1. Using the Octet RED System, the affinity constant (Kd)...Species
Human
1. Using the Octet RED Systemthe affinity constant (Kd) of human VEGFR2-his bound to biotinylated human VEGF165 was 5.9nM. 2. Measured by its ability to inhibit the VEGF-dependent proliferation of human umbilical vein endothelial cells(HUVEC). The ED50 for this effect is typically 10-50μg/mL in the presence of 10 ng/mL recombinant human VEGF165.HEK293 Cells< 1.0 EU per μg of the protein as determined by the LAL method.