ABMIUM target intelligence

LEPR

leptin receptor

Leptin receptor (LEPR), also known as Ob-R or CD295, is a cytokine-receptor-family protein that transduces leptin signals controlling energy balance and broader metabolic physiology. ABMIUM catalogue products linked below support research on LEPR biology.

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OrganismMultiple species; representative: Homo sapiens (Human) NCBI Gene3953 UniProtP48357

ABMIUM research catalogue

Research Products

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Research context & evidence

About LEPR

Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.

Biology

Biological function

Leptin receptor (LEPR/Ob-R/CD295) is the cell-surface receptor for leptin. Ligand binding activates receptor-associated JAK2 and downstream pathways including STAT3 and MAPK signalling, supporting regulation of appetite, energy expenditure, neuroendocrine function and peripheral metabolic responses.

Experimental context

Research context

Leptin receptor (LEPR/Ob-R/CD295) is commonly studied in energy homeostasis, obesity and metabolic research, neuroendocrine signalling and JAK-STAT pathway biology. Use the catalogue filters below to review ABMIUM products associated with LEPR, then confirm species, sample type, assay format, application and product-level validation before use.

Identifiers

Alternative names

Names used across publications, databases and supplier catalogues.

Leptin receptorOb-RCD295DBLEPRDhuB219B219LEPROTLeprbModb1OB-RGRPdiabetesobese-likeoblFa