ABMIUM target intelligence

CTNNB1

catenin beta 1

CTNNB1 identifies catenin beta 1 in Homo sapiens (Human). This target record connects NCBI Gene 1499, UniProtKB P35222 and related ABMIUM catalogue products.

Read full target overview
OrganismMultiple species; representative: Homo sapiens (Human) NCBI Gene1499 UniProtP35222

ABMIUM research catalogue

Research Products

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Research context & evidence

About CTNNB1

Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.

Biology

Biological function

CTNNB1 (beta-catenin) is a key downstream component of canonical Wnt signalling. When stabilised, it can accumulate in the nucleus and act with TCF/LEF transcription factors; it also contributes to cell adhesion as part of cadherin-catenin complexes.

Experimental context

Research context

CTNNB1 is widely studied in Wnt signalling, transcriptional regulation, epithelial cell adhesion, development and cancer models. Reagent selection should consider species, sample type, assay format, application and supporting validation.

Identifiers

Alternative names

Names used across publications, databases and supplier catalogues.

Catenin beta-1β CateninCTNB1CTNNBEVR7MRD19NEDSDVOK/SW-cl.35PRO2286armadilloCatnb