ABMIUM target intelligence
cytotoxic T-lymphocyte associated protein 4
CTLA4 identifies cytotoxic T-lymphocyte associated protein 4 in Homo sapiens (Human). This target record connects NCBI Gene 1493, UniProtKB P16410 and related ABMIUM catalogue products.
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Research context & evidence
Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.
CTLA4 (CD152) is an inhibitory immune receptor expressed by activated T cells and regulatory T cells. It binds the B7 ligands CD80 and CD86 and counterbalances costimulatory signalling, limiting T-cell activation.
CTLA4 is widely studied in T-cell activation, immune checkpoints, regulatory T-cell biology, autoimmunity and tumour immunology. Reagent selection should consider species, cell state, sample type, assay format, application and supporting validation.
Names used across publications, databases and supplier catalogues.
