ABMIUM target intelligence
CD274 molecule
CD274 identifies CD274 molecule in Homo sapiens (Human). This target record connects NCBI Gene 29126, UniProtKB Q9NZQ7 and related ABMIUM catalogue products.
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Research context & evidence
Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.
CD274 (PD-L1) is a ligand for the inhibitory receptor PDCD1/PD-1. It helps maintain immune tolerance by raising the activation threshold of T cells and limiting T-cell effector responses.
CD274 is studied in immune checkpoint signalling, T-cell regulation, peripheral tolerance, tumour immunology and PD-1/PD-L1 pathway biology.
Names used across publications, databases and supplier catalogues.
