ABMIUM target intelligence
argininosuccinate synthase 1
Argininosuccinate synthase 1 (ASS1; argininosuccinate synthase) is a cytosolic urea-cycle enzyme that catalyzes ATP-dependent formation of argininosuccinate from citrulline and aspartate. This catalogue-backed ABMIUM record links human ASS1 (NCBI Gene 445; UniProt P00966) to research reagents.
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Research context & evidence
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ASS1 catalyzes the ATP-dependent condensation of citrulline and aspartate to form argininosuccinate. This reaction is a core urea-cycle step and, together with argininosuccinate lyase, contributes to endogenous arginine biosynthesis.
ASS1 is studied in urea-cycle biology, citrulline and arginine metabolism, nitrogen handling and metabolic pathway regulation. Review each linked ABMIUM product for species, application, assay format and product-level validation before use.
Names used across publications, databases and supplier catalogues.
