ABMIUM target intelligence
amphiregulin
Amphiregulin (AREG) is an epidermal growth factor family ligand produced as a membrane precursor and released as a soluble growth factor. This catalogue-backed ABMIUM record links human AREG (NCBI Gene 374; UniProt P15514) to research reagents for EGFR-ligand biology.
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Research context & evidence
Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.
Amphiregulin (AREG) binds and activates the epidermal growth factor receptor (EGFR), triggering receptor-tyrosine-kinase signalling that supports epithelial-cell proliferation, survival and tissue growth. It functions in autocrine and paracrine signalling and is produced initially as a transmembrane precursor.
AREG is studied in EGFR ligand signalling, epithelial growth and repair, developmental biology and growth-factor responses in tissue and inflammatory models. Review species, assay format, application and product-level validation for each linked ABMIUM reagent.
Names used across publications, databases and supplier catalogues.
