ABMIUM target intelligence
angiopoietin like 3
ANGPTL3 (angiopoietin like 3), also known as angiopoietin-related protein 3 and ANG-5, is a liver-enriched secreted protein studied for its control of lipoprotein lipase activity, triglyceride clearance and systemic lipid metabolism.
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Research context & evidence
Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.
ANGPTL3 is secreted predominantly by the liver and can be proteolytically processed into N- and C-terminal fragments. Reviewed UniProt evidence supports a hepatokine role in lipid and glucose metabolism; ANGPTL3 raises plasma triglycerides in part by inhibiting lipoprotein lipase (LPL), reducing triglyceride clearance. NCBI also describes distinct functional contributions of its N-terminal lipid-metabolism region and C-terminal fibrinogen-like region.
ANGPTL3 is a focused target for research on triglyceride-rich lipoprotein handling, LPL regulation, hepatic control of circulating lipids and familial hypobetalipoproteinemia biology. Select ABMIUM reagents according to species, sample type, assay format, application and product-level validation; catalogue association does not extend target-level biological evidence to every reagent.
Names used across publications, databases and supplier catalogues.
