ABMIUM target intelligence

ANGPTL2

angiopoietin like 2

Angiopoietin-like 2 (ANGPTL2), also known as angiopoietin-related protein 2, is a secreted glycoprotein studied for its effects on endothelial cells and vascular signalling.

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OrganismMultiple species; representative: Homo sapiens (Human) NCBI Gene23452 UniProtQ9UKU9

ABMIUM research catalogue

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Research context & evidence

About ANGPTL2

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Biology

Biological function

ANGPTL2 encodes angiopoietin-related protein 2, a secreted angiopoietin-like glycoprotein. Reviewed UniProt evidence supports induction of endothelial-cell sprouting through autocrine and paracrine action, while NCBI describes homology to angiopoietins and a potential role in endothelial-cell signalling.

Experimental context

Research context

ANGPTL2 is investigated in endothelial and vascular biology, extracellular signalling and models examining autocrine or paracrine responses. Experimental interpretation should account for species, cell type, sample context and assay design when relating ANGPTL2 abundance to biological activity.

Identifiers

Alternative names

Names used across publications, databases and supplier catalogues.

Angiopoietin-related protein 2ANGL2ARP2HARPUNQ170/PRO196