ABMIUM target intelligence
angiopoietin like 2
Angiopoietin-like 2 (ANGPTL2), also known as angiopoietin-related protein 2, is a secreted glycoprotein studied for its effects on endothelial cells and vascular signalling.
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Research context & evidence
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ANGPTL2 encodes angiopoietin-related protein 2, a secreted angiopoietin-like glycoprotein. Reviewed UniProt evidence supports induction of endothelial-cell sprouting through autocrine and paracrine action, while NCBI describes homology to angiopoietins and a potential role in endothelial-cell signalling.
ANGPTL2 is investigated in endothelial and vascular biology, extracellular signalling and models examining autocrine or paracrine responses. Experimental interpretation should account for species, cell type, sample context and assay design when relating ANGPTL2 abundance to biological activity.
Names used across publications, databases and supplier catalogues.