ABMIUM target intelligence

AFM

afamin

Afamin (AFM) is a secreted albumin-family glycoprotein produced mainly by the liver. It is studied as a carrier of hydrophobic ligands, including vitamin E, and as an extracellular factor that can stabilize lipidated Wnt proteins.

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OrganismMultiple species; representative: Homo sapiens (Human) NCBI Gene173 UniProtP43652

ABMIUM research catalogue

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Research context & evidence

About AFM

Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.

Biology

Biological function

Human afamin is a secreted plasma and extravascular-fluid protein in the albumin family. Reviewed UniProt evidence supports binding of vitamin E and a probable carrier role for hydrophobic molecules. Afamin also forms complexes with lipidated Wnt family proteins and can support their solubility and extracellular activity.

Experimental context

Research context

AFM is relevant to research on extracellular ligand transport, vitamin E handling, albumin-family protein biology and Wnt protein stabilization. When selecting an ABMIUM AFM reagent, confirm species, sample type, assay format, application and product-level validation for the intended experiment.

Identifiers

Alternative names

Names used across publications, databases and supplier catalogues.

AfaminAFAMALB2ALBAALFalpha-Alb