ABMIUM target intelligence

ADM

adrenomedullin

Adrenomedullin (ADM; AM) is produced from the pro-adrenomedullin precursor, which also gives rise to proadrenomedullin N-terminal peptide (PAMP). Human ADM is represented by NCBI Gene 133 and reviewed UniProtKB P35318, with related ABMIUM catalogue reagents for research use.

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OrganismMultiple species; representative: Homo sapiens (Human) NCBI Gene133 UniProtP35318

ABMIUM research catalogue

Research Products

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Research context & evidence

About ADM

Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.

Biology

Biological function

The ADM gene encodes pro-adrenomedullin, a precursor processed into biologically active peptides including adrenomedullin and PAMP. Curated NCBI and UniProt records describe adrenomedullin as a vasoactive peptide with potent vasodilatory and hypotensive activity and roles in fluid and electrolyte homeostasis; reviewed UniProt identifies signalling through CALCRL-RAMP2 and CALCRL-RAMP3 receptor complexes.

Experimental context

Research context

ADM/adrenomedullin is studied in vascular signalling, endothelial biology, fluid and electrolyte homeostasis, peptide-hormone biology and angiogenesis-related research. ABMIUM product selection should be based on the specific species, assay format, sample type, application and validation stated for each reagent rather than inferred from target biology.

Identifiers

Alternative names

Names used across publications, databases and supplier catalogues.

AdrenomedullinADMLAMPAMPApH39316RATAP