ABMIUM target intelligence
TNF receptor superfamily member 9
TNF receptor superfamily member 9 (TNFRSF9), also known as 4-1BB or CD137, is an activation-induced costimulatory receptor in immune-cell signalling. ABMIUM catalogue products linked below support research on TNFRSF9/CD137 biology.
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Research context & evidence
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TNF receptor superfamily member 9 (TNFRSF9/CD137/4-1BB) is a member of the TNF receptor superfamily. Following lymphocyte activation, TNFRSF9 signalling can support T-cell clonal expansion, survival and differentiation and engages TRAF-dependent pathways including NF-kappaB. Its activation-linked expression and costimulatory role make CD137/4-1BB widely studied in T-cell and immune-regulation research.
TNFRSF9 (CD137/4-1BB) is commonly studied in T-cell activation, costimulation, immune-cell survival and immuno-oncology research. Use the catalogue filters below to review ABMIUM products associated with TNF receptor superfamily member 9, then confirm species, sample type, assay format, application and product-level validation before use.
Names used across publications, databases and supplier catalogues.
