ABMIUM target intelligence

PCSK9

proprotein convertase subtilisin/kexin type 9

PCSK9 identifies proprotein convertase subtilisin/kexin type 9 in Homo sapiens (Human). This target record connects NCBI Gene 255738, UniProtKB Q8NBP7 and related ABMIUM catalogue products.

Read full target overview
OrganismMultiple species; representative: Homo sapiens (Human) NCBI Gene255738 UniProtQ8NBP7

ABMIUM research catalogue

Research Products

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Research context & evidence

About PCSK9

Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.

Biology

Biological function

PCSK9 is a secreted regulator of plasma cholesterol homeostasis. It binds LDL receptor-family members, including LDLR, and promotes their degradation, reducing receptor recycling to the cell surface.

Experimental context

Research context

PCSK9 is widely studied in cholesterol metabolism, LDLR trafficking, cardiovascular biology and lipid-regulation models. Reagent selection should consider species, sample type, assay format, application and supporting validation.

Identifiers

Alternative names

Names used across publications, databases and supplier catalogues.

Proprotein convertase subtilisin/kexin type 9FH3FHCL3HCHOLA3LDLCQ1NARC-1PC9PSEC0052