ABMIUM target intelligence

FAS

Fas cell surface death receptor

FAS identifies Fas cell surface death receptor in Homo sapiens (Human). This target record connects NCBI Gene 355, UniProtKB P25445 and related ABMIUM catalogue products.

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OrganismMultiple species; representative: Homo sapiens (Human) NCBI Gene355 UniProtP25445

ABMIUM research catalogue

Research Products

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Research context & evidence

About FAS

Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.

Biology

Biological function

FAS (CD95) is a death receptor for FASLG. Ligand-induced receptor activation recruits FADD and CASP8 into a death-inducing signalling complex, initiating a caspase cascade that can drive apoptosis.

Experimental context

Research context

FAS is studied in apoptosis, immune-cell homeostasis, peripheral tolerance and death-receptor signalling.

Identifiers

Alternative names

Names used across publications, databases and supplier catalogues.

Tumor necrosis factor receptor superfamily member 6CD95ALPS1AAPO-1APT1FAS1FASTMTNFRSF6TNR6FasRTNFR6lpr