ABMIUM target intelligence
Fas cell surface death receptor
FAS identifies Fas cell surface death receptor in Homo sapiens (Human). This target record connects NCBI Gene 355, UniProtKB P25445 and related ABMIUM catalogue products.
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Research context & evidence
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FAS (CD95) is a death receptor for FASLG. Ligand-induced receptor activation recruits FADD and CASP8 into a death-inducing signalling complex, initiating a caspase cascade that can drive apoptosis.
FAS is studied in apoptosis, immune-cell homeostasis, peripheral tolerance and death-receptor signalling.
Names used across publications, databases and supplier catalogues.