ABMIUM target intelligence

ERBB3

erb-b2 receptor tyrosine kinase 3

Erb-b2 receptor tyrosine kinase 3 (ERBB3), also known as HER3, is an EGFR-family receptor that forms signalling heterodimers with other ERBB receptors. ABMIUM catalogue products linked below support research on ERBB3/HER3 biology.

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OrganismMultiple species; representative: Homo sapiens (Human) NCBI Gene2065 UniProtP21860

ABMIUM research catalogue

Research Products

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Research context & evidence

About ERBB3

Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.

Biology

Biological function

Erb-b2 receptor tyrosine kinase 3 (ERBB3/HER3) is an EGFR-family transmembrane receptor with impaired intrinsic kinase activity that signals through heterodimerisation with other ERBB receptors. Ligands including neuregulins promote receptor complex formation and downstream pathways such as PI3K-AKT, supporting cell growth, survival and differentiation.

Experimental context

Research context

ERBB3/HER3 is commonly studied in growth-factor signalling, EGFR/ERBB receptor networks, PI3K-AKT biology and cancer research. Use the catalogue filters below to review ABMIUM products associated with erb-b2 receptor tyrosine kinase 3, then confirm species, sample type, assay format, application and product-level validation before use.

Identifiers

Alternative names

Names used across publications, databases and supplier catalogues.

HER3Receptor tyrosine-protein kinase erbB-3FERLKLCCS2MDA-BF-1VSCN1c-erbB-3erbB3-Sp180-ErbB3p45-sErbB3p85-sErbB3