ABMIUM target intelligence
erb-b2 receptor tyrosine kinase 2
ERBB2 identifies erb-b2 receptor tyrosine kinase 2 in Homo sapiens (Human). This target record connects NCBI Gene 2064, UniProtKB P04626 and related ABMIUM catalogue products.
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Research context & evidence
Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.
ERBB2 (HER2) is a receptor tyrosine kinase in the EGFR/ERBB family. It has no known direct activating ligand and acts as a preferred heterodimerisation partner for other ligand-bound ERBB receptors, amplifying downstream signalling controlling cell proliferation, survival and differentiation.
ERBB2 is widely studied in receptor tyrosine-kinase signalling, epithelial biology, cell proliferation and cancer models. Reagent selection should consider expression level, phosphorylation or activation state, species, sample type, assay format, application and supporting validation.
Names used across publications, databases and supplier catalogues.
