ABMIUM target intelligence
complement C1q binding protein
C1QBP (complement C1q binding protein), also known as p32, gC1qR and HABP1, is a multifunctional protein studied in complement regulation, mitochondrial protein synthesis and RNA-associated cellular processes.
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Research context & evidence
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C1QBP is a multifunctional, predominantly mitochondrial protein with established roles in mitochondrial ribosome function and protein synthesis. NCBI-curated evidence also describes binding to the globular heads of complement C1q and inhibition of C1 activation. Its p32, gC1qR and HABP1 names reflect experimental contexts reported for the same protein.
C1QBP is used in research on complement and C1q biology, mitochondrial translation and ribosome function, RNA-associated processes, inflammation and cellular stress. Experimental interpretation should distinguish mitochondrial from cell-surface or other extramitochondrial contexts and account for species, sample type and assay format.
Names used across publications, databases and supplier catalogues.
