ABMIUM target intelligence
BCL10 immune signaling adaptor
BCL10 encodes an immune-signalling adaptor that links CARD-domain proteins to downstream inflammatory signalling. This target record connects reviewed human BCL10 identifiers and aliases with ABMIUM catalogue products targeting BCL10.
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Research context & evidence
Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.
BCL10 has a key role in adaptive and innate immune signalling. It bridges CARD-domain-containing proteins, including CARD9, CARD11 and CARD14, to downstream pathways that activate NF-kappa-B and p38 MAP-kinase signalling, supporting expression of pro-inflammatory cytokine and chemokine genes.
BCL10 is studied in antigen-receptor and innate immune signalling, NF-kappa-B pathway activation, inflammatory responses and lymphoid malignancy. Experimental interpretation should consider stimulus, cell lineage, signalling-complex context, subcellular localisation and cleavage or modification state, alongside species, application and product-level validation.
Names used across publications, databases and supplier catalogues.
