ABMIUM target intelligence
autophagy related 12
ATG12 (autophagy related 12) encodes ubiquitin-like protein ATG12, a core autophagy factor that forms the ATG12-ATG5 conjugate required for autophagosome membrane formation.
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Research context & evidence
Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.
Ubiquitin-like protein ATG12 is covalently conjugated to ATG5 through an ATG7- and ATG10-dependent system. The ATG12-ATG5 complex, together with ATG16L1, acts as an E3-like factor that promotes ATG8-family lipidation and association with developing autophagic membranes.
ATG12 is widely studied in autophagosome biogenesis, lysosomal stress responses and autophagy-dependent cellular adaptation. Use ABMIUM ATG12 catalogue products with application-, species- and validation-specific product data when designing autophagy experiments.
Names used across publications, databases and supplier catalogues.
