ABMIUM target intelligence
activating transcription factor 1
Activating transcription factor 1 (ATF1), reviewed by UniProt as cyclic AMP-dependent transcription factor ATF-1, is a bZIP transcription factor that links cAMP/PKA signalling to CRE-dependent gene regulation. Human ATF1 maps to NCBI Gene 466 and reviewed UniProtKB P18846; this record links the verified target to related ABMIUM catalogue products.
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Research context & evidence
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ATF1 binds cAMP response elements (CREs) in promoters and mediates PKA-responsive transcription. Phosphorylation within its kinase-inducible domain enhances transactivation, supporting stimulus-responsive regulation of gene expression.
ATF1 is studied in cAMP/PKA signalling, CRE-dependent transcription, bZIP transcription-factor biology and phosphorylation-dependent transcriptional control. Select related ABMIUM products only after confirming species, sample type, assay/application and product-level validation.
Names used across publications, databases and supplier catalogues.
