ABMIUM target intelligence
angiogenin
Angiogenin (ANG), also known as ribonuclease 5 (RNase 5), is a secreted ribonuclease studied for its roles in angiogenesis, RNA metabolism and cellular stress responses.
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Research context & evidence
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ANG encodes angiogenin, a secreted member of the pancreatic RNase A family. Curated NCBI and reviewed UniProt evidence supports its ribonuclease activity, promotion of endothelial angiogenic responses, nucleolar stimulation of ribosomal RNA transcription and stress-dependent cleavage of cellular tRNAs that can influence protein synthesis.
ANG is studied in vascular biology, ribonuclease-dependent signalling, RNA metabolism and cellular stress responses. Experimental interpretation should distinguish extracellular angiogenic effects from intracellular RNA-processing functions and account for species, cell state, sample type and assay format.
Names used across publications, databases and supplier catalogues.
