ABMIUM target intelligence
alkaline phosphatase, placental
ALPP (alkaline phosphatase, placental), commonly called placental alkaline phosphatase (PLAP), encodes a placental-type alkaline phosphatase studied in phosphomonoesterase activity, placental biology and lineage-associated expression.
Read full target overviewABMIUM research catalogue
Loading products for ALPP…
Research context & evidence
Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.
Placental alkaline phosphatase is a metalloenzyme that hydrolyses phosphate monoesters. The mature ALPP/PLAP enzyme functions as a homodimer and uses metal cofactors at its catalytic site, making it a useful target for studying extracellular alkaline-phosphatase activity and placental-type phosphatase biology.
ALPP/PLAP is studied in placental and trophoblast biology, differentiation-linked expression and alkaline-phosphatase family biochemistry. Because closely related alkaline phosphatases can share sequence and biochemical features, researchers should confirm reagent specificity, species, sample type and application at product level.
Names used across publications, databases and supplier catalogues.
