ABMIUM target intelligence
aldehyde dehydrogenase 1 family member A1
ALDH1A1 encodes aldehyde dehydrogenase 1 family member A1, the reviewed human protein aldehyde dehydrogenase 1A1. This cytosolic NAD-dependent enzyme oxidizes a broad range of aldehydes and also converts retinaldehyde to retinoic acid, linking aldehyde metabolism with vitamin A/retinoid biology.
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Research context & evidence
Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.
ALDH1A1 catalyses the irreversible oxidation of aldehydes to their corresponding carboxylic acids. Reviewed UniProt supports a role downstream of retinol dehydrogenases in converting retinaldehyde to retinoic acid, the second oxidation step from retinol/vitamin A to retinoic acid.
ALDH1A1 is studied in aldehyde metabolism, retinoid signalling, oxidative and metabolic stress, and cell-state research. Experimental interpretation can depend on species, tissue, assay and isozyme specificity, so product-level validation should be confirmed for each ABMIUM reagent.
Names used across publications, databases and supplier catalogues.
