ABMIUM target intelligence
ADAM metallopeptidase with thrombospondin type 1 motif 13
ADAM metallopeptidase with thrombospondin type 1 motif 13 (ADAMTS13/ADAMTS-13), also known as von Willebrand factor-cleaving protease (vWF-CP), is a secreted plasma metalloprotease central to von Willebrand factor regulation.
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Research context & evidence
Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.
ADAMTS13 is the von Willebrand factor-cleaving metalloprotease. Reviewed UniProt describes cleavage of von Willebrand factor (VWF) multimers into smaller forms, thereby limiting VWF-mediated platelet thrombus formation under shear conditions.
ADAMTS13 is studied in haemostasis, thrombosis, von Willebrand factor processing and thrombotic thrombocytopenic purpura (TTP). Reagent selection should be based on species, sample type, assay format, application and product-level validation.
Names used across publications, databases and supplier catalogues.
