ABMIUM target intelligence

ADAMTS1

ADAM metallopeptidase with thrombospondin type 1 motif 1

ADAM metallopeptidase with thrombospondin type 1 motif 1 (ADAMTS1/ADAMTS-1), also known as METH-1, is a secreted extracellular metalloprotease. This ABMIUM guide connects its verified identity to catalogue-backed research products and authoritative NCBI/UniProt evidence.

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OrganismMultiple species; representative: Homo sapiens (Human) NCBI Gene9510 UniProtQ9UHI8

ABMIUM research catalogue

Research Products

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Research context & evidence

About ADAMTS1

Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.

Biology

Biological function

ADAMTS1 is a secreted metalloprotease of the ADAMTS family. Reviewed UniProt reports cleavage of extracellular-matrix substrates including aggrecan and cartilage oligomeric matrix protein (COMP), together with anti-angiogenic activity and a proposed role in follicular rupture.

Experimental context

Research context

ADAMTS1 is studied in extracellular-matrix remodelling, proteoglycan turnover, cartilage biology, angiogenesis and reproductive tissue biology. Reagent selection should be based on species, sample type, assay format, application and product-level validation.

Identifiers

Alternative names

Names used across publications, databases and supplier catalogues.

A disintegrin and metalloproteinase with thrombospondin motifs 1ATS1C3-C5KIAA1346METH1ADAMTSADAMTS-1METH-1