ABMIUM target intelligence
actinin alpha 1
Actinin alpha 1 (ACTN1), encoding alpha-actinin-1, is a non-muscle cytoskeletal actin-binding protein. This target record connects human NCBI Gene 87, reviewed UniProtKB P12814 and related ABMIUM catalogue products.
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Research context & evidence
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Alpha-actinin-1, encoded by ACTN1 (actinin alpha 1), is an F-actin cross-linking protein that helps anchor actin filaments to intracellular structures. In non-muscle cells it contributes to microfilament bundles and adherens-type junctions; reviewed UniProt also curates an IGSF8-associated role in immune-synapse formation and efficient T-cell activation.
ACTN1 research spans actin-cytoskeleton architecture, cell adhesion, junctional organisation, cell motility, platelet biology and immune-synapse signalling. ABMIUM catalogue products associated with ACTN1 can support target-focused studies; confirm species, sample type, application and reagent-level validation before use.
Names used across publications, databases and supplier catalogues.
