ABMIUM target intelligence
actin alpha 2, smooth muscle
Actin alpha 2, smooth muscle (ACTA2), commonly described as smooth muscle alpha-actin and reviewed by UniProt as actin, aortic smooth muscle, is a contractile actin isoform. This record connects NCBI Gene 59, UniProtKB P62736 and related ABMIUM catalogue products.
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Research context & evidence
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Actin alpha 2, smooth muscle (ACTA2; smooth muscle alpha-actin) is a highly conserved actin isoform and a major component of the smooth-muscle contractile apparatus. It contributes to cytoskeletal structure and cell motility and has an established role in vascular contractility and blood-pressure homeostasis.
ACTA2 research is relevant to smooth-muscle differentiation, vascular contractility, cytoskeletal organisation, vessel-wall biology and tissue remodelling. ABMIUM catalogue products associated with ACTA2 can support target-focused studies; confirm species, sample type, application and product-level validation for the selected reagent.
Names used across publications, databases and supplier catalogues.
