ABMIUM target intelligence
angiotensin converting enzyme 2
Angiotensin-converting enzyme 2 (ACE2; also known as ACEH) is a membrane-associated metallopeptidase in the renin-angiotensin system. This target record connects human NCBI Gene 59272, reviewed UniProtKB Q9BYF1 and related ABMIUM catalogue products.
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Research context & evidence
Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.
Angiotensin-converting enzyme 2 (ACE2) is a counter-regulatory carboxypeptidase of the renin-angiotensin system. It converts angiotensin I to angiotensin-(1-9) and angiotensin II to angiotensin-(1-7), helping counterbalance classical angiotensin II signalling and supporting cardiovascular homeostasis. ACE2 also functions as a cellular receptor for HCoV-NL63, SARS-CoV and SARS-CoV-2 spike proteins.
ACE2 research spans renin-angiotensin signalling, cardiovascular and renal homeostasis, peptide processing, epithelial and endothelial biology, and coronavirus entry mechanisms. ABMIUM catalogue products associated with ACE2 can support target-focused studies; species, sample type, application and product-level validation should be confirmed on the individual product page.
Names used across publications, databases and supplier catalogues.
