ABMIUM target intelligence
ATP binding cassette subfamily G member 2 (JR blood group)
ATP binding cassette subfamily G member 2 (ABCG2), also called breast cancer resistance protein (BCRP) or CD338, is a broad-substrate ATP-dependent efflux transporter represented in the ABMIUM catalogue.
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Research context & evidence
Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.
ABCG2/BCRP is a broad-substrate ATP-dependent transporter that exports physiological compounds, dietary toxins and xenobiotics from cells. It contributes to multidrug resistance and also participates in transport of porphyrins, heme and urate.
ABCG2 is studied in drug transport and resistance, barrier and placental transport, xenobiotic handling, porphyrin and heme homeostasis, and urate biology. Reagent selection should consider species, membrane localization, application and product-level validation.
Names used across publications, databases and supplier catalogues.
